Bio computers use biologically derived molecules — such as DNA and proteins — to perform digital or real computations. This is made possible by nanobiotechnology. They can be biochemical, biomechanical or bioelectronic. All biological organisms have the ability to self-replicate and self-assemble into functional components. The economical benefit of biocomputers lies in this potential. They use transcriptors which are transistor-like devices composed of DNA and RNA rather than a semiconducting material such as silicon.
DNA digital data storage is the process of encoding and decoding binary data to and from synthesized strands of DNA. It has very high storage density; 0.36 zettabytes can be stored in 1 gram of DNA. In 2019, all 16 GB of text from Wikipedia was encoded into synthetic DNA using genomics.
This is early technology eventually used to make bioships.
A wetware computer is an organic computer (or artificial organic brain or neurocomputer) composed of organic material "wetware" such as "living" neurons (as opposed to artificial neural networks). Wetware computers composed of neurons are different than conventional computers because they are thought to be capable in a way of "thinking for themselves", because of the dynamic nature of neurons. Dryware would refer to a non-biological part of a computer or cyborg.
Bio-neural gel packs from Star Trek had fibers capable of making billions of connections, thus generating a sophisticated and responsive computing architecture. This allowed computers to "think" in very similar ways to living organisms; by using "fuzzy logic", they could effectively operate by making a "best guess" answer to complex questions rather than working through all possible calculations.